DESIGN AND DEVELOPMENT OF TELMISARTAN FAST DISSOLVING FILM
Pandya Ketul
Department of Pharmaceutics, Shri B. M. Shah Collage of Pharmaceutical Education and Research, Modasa
Kanu Patel
Department of Pharmaceutics, Shri B. M. Shah Collage of Pharmaceutical Education and Research, Modasa
Mukesh Patel
Department of Pharmaceutics, Shri B. M. Shah Collage of Pharmaceutical Education and Research, Modasa
N.M. Patel
Department of Pharmaceutics, Shri B. M. Shah Collage of Pharmaceutical Education and Research, Modasa
In the present study fast dissolving film of Telmisartan was prepared using Pullulan as film forming polymer. To decreases the disintegration time Microcrystalline cellulose was used as filler. All the films were evaluated for their Thickness, Folding endurance, Tensile strength, % elongation, Disintegration time, In vitro drug release, and Stability study. The formulation F9 shows higher drug content (93.9%),Less Disintegration Time (33sec), Tensile Strength and Folding endurance respectively 0.249 N/mm 2 and 243. Film of batch F9 was disintegrated with 33 second, Releases 93.22% drug within 16 minutes during the in vitro dissolution test and there was no significant change is shown during stability study
4 , 1 , 2014
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