SELECTION OF FORMULATION AND EVALUATION OF CISPLATIN NANOPARTICLES BY USING ANALYTIC HIERARCHY PROCESS

J. Bhavani
Bundelkhand University, Jhansi– 28412, Uttar Pradesh, India
Sunil Kumar Prajapati
Bundelkhand University, Jhansi– 28412, Uttar Pradesh, India
S. Ravichandran
PSV College of Pharmaceutical Science and Research, Krishnagiri – 635108, Tamil Nadu, India.

Cisplatin ,Nanoparticles ,Analytic Hierarchy Process , Paricle size ,Polydispersity Index ,Zeta Potential ,Natural polymer ,Formulation and Evaluation ,

The objective of this study was to choice finest technique for the development of cisplatin nanoparticles encompass natural polymer particles using Analytic Hierarchy Process (AHP). The method of selection may lead to waste of time, loss of products and monetary resources. The possibility to overcome these problems, AHP was employed to discovery the appropriate method. In the AHP, a choice of hierarchy was built with a goal for alternatives. After constructing the AHP, the expert choice software was used to compute the overall priority of criteria, sub-criteria and alternatives. The best alternative selected was founded on the highest priority. Based on the Nanoscale to formulate and evaluate cisplatin nanoparticles encompass natural polymer particles and it shows the particle size Polydispersity Index and zeta potential were within acceptable limits. Drug content and entrapment efficiency were 98.16% and 85.67%, respectively. This study concludes that the AHP was feasible and real tool for choosing a most suitable method for the formulation and evaluation of cisplatin nanoparticles.

8 , 2 , 2018