FORMULATION AND EVALUATION OF IMMEDIATE RELEASE SORAFENIB TOSYLATE TABLETS
P.Nithin
Scient institute of Pharmacy, Department of Pharmaceutics, Ibrahimpatnam, Hyderabad- 501506, Andhra Pradesh- India.
V.Susheel
Scient institute of Pharmacy, Department of Pharmaceutics, Ibrahimpatnam, Hyderabad- 501506, Andhra Pradesh- India.
G.Rajnikanth
Scient institute of Pharmacy, Department of Pharmaceutics, Ibrahimpatnam, Hyderabad- 501506, Andhra Pradesh- India.
The aim of present work is to formulate and evaluate immediate release Sorafenib tosylate tablets. Objective of the present work is to develop a solid oral dosage form of Sorafenib tosylate & its comparison with innovator drug (Nexavar). The formulation of tablets were done to match the in-vitro drug release with respect to the reference drug & carry out the stability studies as per the guidelines.
4 , 3 , 2014
182 - 186