123DESIGN AND EVALUATION OF GLIPIZIDE AND TELMISARTAN BILAYER FLOATING TABLETSThe XM 12 Bi-Layer Tablet Press features a retractable second layer feeder that permits automated first layer sampling at production speeds. The first layer sampling capability also offers a hardening feature, in which the main compression station will automatically compress the first layer tablet for in-process measurement. The two feeders are zero clearance and are configured with an integrated dust extraction manifold which cleans the die table and completely eliminates any potential for cross contamination. WipCon® solution available for potent for Small-Scale Bi-layer Applications. The KORSCH XM 12 Bi- Layer Tablet Press is a small-scale press which is ideal for product development scale-up, clinical trials and midrange production. The bi-layer execution, single-layer conversion kit and exchangeable turret offer unprecedented flexibility. The XM 12 Bi-Layer Tablet Press offers a new standard in GMP with extreme accessibility to the compression zone and a combination of quick disconnects and smooth surfaces that permit fast cleaning and changeover. The machine features a 5 KN tamping station, 40 KN precompression station, 80 KN main compression station, and a unique structural design that eliminates vibration to the head piece and base frame. The result is an extreme reduction in the operating noise level.rajskr321@gmail.comResearch912019Glipizide, Telmisartan, Bilayer Floating Tablets, Evaluation.Rajasekhar R,Umasankar K,Jayachandra Reddy PRajasekhar R,Umasankar K,Jayachandra Reddy P