63FORMULATION AND EVALUATION OF IMMEDIATE RELEASE SORAFENIB TOSYLATE TABLETSThe aim of present work is to formulate and evaluate immediate release Sorafenib tosylate tablets. Objective of the present work is to develop a solid oral dosage form of Sorafenib tosylate & its comparison with innovator drug (Nexavar). The formulation of tablets were done to match the in-vitro drug release with respect to the reference drug & carry out the stability studies as per the guidelines.Nithinpallepati@gmail.com Research432014Sorafenib Tosylate,Immediate Release,Formulation,Evaluation,ComparisonP.Nithin,V.Susheel ,G.RajnikanthScient institute of Pharmacy, Department of Pharmaceutics, Ibrahimpatnam, Hyderabad- 501506, Andhra Pradesh- India.,Scient institute of Pharmacy, Department of Pharmaceutics, Ibrahimpatnam, Hyderabad- 501506, Andhra Pradesh- India.,Scient institute of Pharmacy, Department of Pharmaceutics, Ibrahimpatnam, Hyderabad- 501506, Andhra Pradesh- India.